Current Research in Medical Sciences

en Mental Health and Quality of Life Among Iranian Women with Anogenital Warts روانشناسی روانشناسی پژوهشی اصیل Original Article Background: Anogenital warts may impair health-related quality of life (HRQoL) and mental health, yet data in Iranian women are scarce. We compared HRQoL and mental health between women with and without anogenital warts in Babol, Iran. Methods: This cross-sectional case–control study (February–September 2022) recruited a single-centre convenience sample of 108 women aged 18–65 years (54 dermatologist-confirmed cases; 54 controls without current or prior warts). Participants completed the 36-Item Short Form Health Survey (SF-36) and the Brief Symptom Inventory-53 (BSI-53). Analyses were conducted in IBM SPSS Statistics (version 22) using two-sided tests; p < 0.05 was considered statistically significant. Results: Mean age was similar in cases and controls (30.57±7.69 vs 31.74±9.62; p=0.488). Compared with controls, cases had lower SF-36 physical functioning (p=0.014), role limitations due to physical health (p=0.036), bodily pain (p=0.001), and Physical Component Summary scores (p=0.012). BSI-53 subscales and total score did not differ between groups (total p=0.801). Within cases, HPV-risk groups differed for SF-36 Bodily Pain and BSI-53 Depression (omnibus p=0.013 and 0.049). High-risk women had worse pain (59.25±23.95 vs 77.50±16.29) and higher Depression scores (8.23±6.36 vs 2.70±3.30) than low-risk women (Bonferroni p=0.048 and 0.044). Lower Bodily Pain scores indicate more severe pain. Conclusion: Anogenital warts were associated with poorer physical HRQoL, while general psychological symptom scores were comparable between groups. High-risk HPV status may help identify women who could benefit from pain-focused management and brief distress screening; longitudinal multicentre studies are warranted.   Papillomavirus Infections, Quality of Life, Mental Health, Women, Iran 15 23 http://crms.mubabol.ac.ir/browse.php?a_code=A-10-275-1&slc_lang=en&sid=1 Mahasti Emami Hamzehkolaee mahastiemami1@gmail.com 10031947532846002839 10031947532846002839 No Clinical Research Development Unit of Shahid Yahyanejad Hospital, Babol University of Medical Sciences, Babol, Iran Azar Shirzadian Kebria shirzadiank@gmail.com 10031947532846002840 10031947532846002840 Yes Department of Dermatology, School of Medicine, Babol University of Medical Sciences, Babol, Iran. Parnia Ghasemzadeh parnia.ghaasemzadeh@gmail.com 10031947532846002841 0009-0001-2475-8348 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Sakineh Javadian Koutanaei javadian1939@yahoo.com 10031947532846002842 10031947532846002842 No Department of Psychiatry, School of Medicine, Babol University of Medical Sciences, Babol, Iran. Hoda Shirafkan Hoda Shirafkan Hodashirafkan@gmail.com 10031947532846002843 10031947532846002843 No Department of Community Medicine, School of Medicine Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran