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Currently, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the etiological factor of the coronavirus disease 2019 (COVID-19) pandemic condition. Based on the evidence, the number of infected patients is increasing around the world. SARS-COV2 infection could show both pulmonary and extra-pulmonary manifestations in patients. The Influenza virus is the cause of influenza disease which is a seasonal viral disease with clinical symptoms similar to COVID-19. Influenza could be a major public health problem throughout the world, as each year approximately 10%‐20% of the worldchr('39')s population are infected and is the major cause of death, particularly among the elderly. Since influenza has an effective and preventive vaccine, maximizing influenza vaccination has been suggested. Until now (November 20, 2020) COVID-19 doesn’t have any approved drug or vaccine, So the universal influenza vaccination will probably decrease the health burden of this co-infection. In this review, we will focus on the importance of COVID-19 and influenza co-infection in the COVID-19 pandemic era.

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Background and Objective: In humans, viruses cause respiratory infections that are usually mild, including the common cold, or sometimes it can be fatal. The outbreak of coronavirus disease 2019 (COVID-19) occurred in Wuhan, China was more expansive than initially estimated, with cases now confirmed in several countries. Therefore, it is crucial to determine the clinical symptoms of COVID-19 in different age groups.
Methods: This cross-sectional study evaluated the presence of SARS-CoV-2 infection in 219 throat and nasal swab samples using Real-time PCR. All samples were collected from people with respiratory symptoms who went to the grand bazaar.
Findings: Of 219 patients examined, 19 (8.6%) positive cases out of 219 for SARS-CoV-2 were found by using Real-time PCR. Among these 19 positive cases of SARS-CoV-2, 6 (2.7%) were under 5, 3 (1.3%) were between 5-18, 4 (1.8%) were between 18-50 and 6 (2.7%) were over 50 years old respectively. Most common symptoms in positive group was cough (89%) and despite other age groups, in patients over 50 years old, myalgia and diarrhea was common.
Conclusion: It seems that SARS-CoV-2 symptoms can vary in different age groups but unlike other age groups, in elderly, uncommon symptoms like eyes redness, myalgia and diarrhea seems is seen following COVID-19 infection

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Background: Human Papillomaviruses (HPVs) are common sexually transmitted viruses that cause health problems, including genital warts and different type of cancers. There are over 200 different types of HPV, some of which are correlated with the progress of cervical cancer. One of the HPV genes responsible for its oncogenic potential is the E6 gene. E6 is a critical protein in the life cycle of HPV and a key contributor to the development of HPV-associated cancers. Its interactions with cellular proteins lead to disruptions in key cellular pathways and the promotion of cancerous cell growth. Overall, HPV E6 represents a reassuring target for the expansion of novel therapies for the treatment of HPV-associated cancers and understanding its molecular interactions with host proteins is critical for developing targeted therapies for HPV-associated cancers. In this article, we will focus on the cancer-related mechanism and cell interaction of HPV E6.