|
|
 |
Search published articles |
 |
|
Showing 4 results for Jafarian
Ali Zabihi, Seyedeh Roghayeh Jafarian Amiri, Leila Valizadeh, Vahid Zamanzadeh, Volume 1, Issue 1 (NHJ 2016)
Abstract
Background and Objective: Hepatitis B is one of the most common health problems in the world, especially in developing countries. It is necessary to understand and be aware of what infected people experience in their lives with this phenomenon. The purpose of the present study was to determine the experiences of concealment of the disease perceived by these patients.
Methods: This study was a qualitative content analysis. The data was collected through 18 unstructured and in-depth interviews with hepatitis B carriers in healthcare centers and consultation centers for liver and digestive diseases in Amol, Babol and Tabriz, during 2014-2015. The sampling was purposive and all of the interviews were recorded, transcribed word by word and analyzed using conventional qualitative content analysis.
Findings: The data analysis led to extraction of concealment of disease, as the major theme, along with three sub-themes, including feigning normal social behavior, minimization of the disease and disease concealment (living with secrets). Analysis of participants’ experiences showed that one of the common and important experiences among them was concealment of disease to persist their interactions, which existed as different forms in various states and situations of their lives.
Conclusion: According to the results, patients infected by hepatitis B virus have to hide their diseases from other people in order to continue their normal lives and protect themselves against the negative and humiliating glances of others. Consequently, it should be emphasized on the necessity of educational and consultation programs regarding the different aspects of this disease, as well as appropriately informing the society.
Farzaneh Jafarian, Tahmineh Gorgani-Firouzjaee, Volume 1, Issue 2 (11-2016)
Abstract
Abstract
Background and Objective: According to suitable ecological conditions and being endemic of Mazandaran province for many parasitic agents, present study was done for determination of rate of parasitic infections in patients referred to Ayatollah Rohani hospital in 2015.
Methods: This cross-sectional descriptive- analytical study was performed on 4478 fecal samples were collected from patients referred to Ayatollah Rohani hospital between April 2015 and March 2016. The samples were examined with direct wet mount and formalin-ether concentration methods. The data were analyzed using Chi-square tests and SPSS.
Findings: Of the 4478 samples studied, 370 (8.26%) were positive for parasitic infection. Entamoeba histolytica, Entamoeba coli and Giardia lamblia were the most common causes with the prevalence of 2.56%, 1.6% and 1.45%, respectively. The infection rate in male was higher than from female (p<0.05). Rate of infections in rural areas in comparison to urban regions did not showed any significant differences. Most of the infections were seen in autumn compared with other seasons (p=0.02). Infection rate was more common in 31-49 age group and lower infection rate was observed in age group of less than 11 years (p=0.025).
Conclusion: According to prevalence of parasitic infection in Babol, which are important in terms of medical and clinical aspects, thus using an effective controlling systems is proposed for decreasing food and water contaminations.
Fatemeh Kelich, Mojtaba Qanbari Qalehsari, Ali Zabihi, Afsaneh Arzani, Seyedeh Roghayeh Jafarian_amiri, Navid Danaee, Volume 7, Issue 2 (9-2023)
Abstract
Background: Covid-19 is a disease with different characteristics, ranging from symptomless carriers to death due to complications, which can induce a significant amount of stress. Resilience is very important for coping with stress and maintaining balance. The aim of this study was to investigate the relationship between resilience and clinical symptoms in patients with Covid-19.
Methods: This cross-sectional descriptive analytical study was conducted in 2022, with the participation of 100 patients hospitalized at Shahid Beheshti, Yahya Nejad, and Rouhani hospitals in Babol city, as well as Kausar hospital in Semnan city, who had received positive PCR test results and a definite diagnosis of Covid-19. They were selected using a convenience sampling method. Data collection tools included demographic information, a symptom checklist, clinical information, the Mini Mental Status Questionnaire (MMSE), and the Connor-Davidson Resilience Scale (CD-RISC)-10.
Results: The mean age of the patients was 53±15.3 years, and 91% of them were married. Seventy-eight percent of the patients had a headache, 83% had a cough, and 88% had dyspnea. There was no significant difference in resilience scores between patients with symptoms and those without symptoms (P>0.05). The multiple regression model revealed no significant relationship between disease symptom severity and resilience levels, even when considering the confounding variables (P>0.05).
Conclusion: The absence of a relationship between Covid-19 symptoms and resilience may be attributed to the complex nature of the disease and the multidimensional aspect of resilience. We suggest conducting more comprehensive research on various facets of resilience and its mechanisms of impact on diseases in diverse contexts, with larger sample sizes.
Dr Elham Jafarian, Dr Mahmood Monadi, Dr Hoda Shirafkan, Dr Hamed Mehdinezhad, Volume 9, Issue 1 (4-2025)
Abstract
Background: The severe form of coronavirus disease 2019 (COVID-19) is mainly marked by hyper inflammation and the associated multi-organ damage it causes. Baricitinib has been shown to have dual anti-inflammatory and antiviral effects. Our study aims to evaluate the effect of adding Baricitinib to the standard treatment on clinical and laboratory outcomes in patients with COVID-19 pneumonia.
Methods: In this retrospective cohort study conducted at three tertiary hospitals affiliated with Babol University of Medical Sciences, the medical records of 129 adult patients with severe COVID-19 pneumonia were reviewed. Patients were divided into two groups: one received standard treatment with remdesivir and corticosteroids, and the other received Baricitinib (4 mg daily for up to 14 days) in addition to the standard treatment. Outcomes included duration of hospital stay, 14- and 28-day mortality, arterial oxygen saturation, disease severity, invasive ventilation need, and ICU admission.
Results: Among the 129 patients (mean age 55.33 ± 14.88 years; 34.1% men), the Baricitinib group showed significantly lower disease severity at 14 days (p=0.02), reduced 14-day (0/66 vs 8/63, p=0.003) and 28-day mortality (1/66 vs 9/63, p=0.008), and greater arterial oxygen saturation improvement (p<0.001). The ICU and invasive ventilation duration did not differ between the two groups (p = 0.58 and p = 0.99, respectively).
Conclusion: This study found that adding Baricitinib to the standard treatment in severe COVID-19 pneumonia could reduce mortality and disease severity and improve arterial blood oxygen saturation compared to standard treatment only
|
|