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Background and Objective: Cytomegalovirus (CMV) is the most important cause of congenital viral infections that can lead to sensorineural hearing loss and mental retardation in children. After infection of the human, CMV remains latent and can be transmitted to others. This study was performed to determine the seroprevalence of CMV infection among the students of Babol University of Medical Sciences.

Methods: This cross-sectional study was conducted on 178 students of Babol University of Medical Sciences during 2009-2012. After obtaining the informed consent, demographic data and blood samples were collected from all participants. Anti-CMV IgG antibody titers were measured by ELISA. The collected data were analyzed by SPSS and statistical tests.

Findings: Of the participants, 37 (20.8%) were male and others were female. The mean age was 21.29+2.91. About 96% of the subjects (171 students) were positive for anti-CMV IgG, of whom 33 (19.3%) were male and others were female. There was no significant association between anti-CMV antibodies and demographic variables including gender (p=0.74), marital status (p=0.684), residency status (p>0.05), and field of study (p=0.95).

Conclusion: According to the high prevalence of CMV among the medical sciences students and the importance of congenital diseases caused by CMV, expansion of prevention programs and essential trainings, especially for the seronegative healthcare workers (e.g. physicians, nurses and midwives) and women in the marriageable age, seems necessary.

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Although brain abscess is not a very common infection , it is very life-threatening if it occures.Most brain abscesses in children are the result of ear,sinus or tooth infection.In this study,we report an eleven year old girl with a huge brain abscess due to mastoiditis.Despite exesive size of brain abscess and towice surgical intervention,our case cured without any neurological sequela.

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 Introduction The COVID-19 can cause a broad spectrum of neurologic and systemic manifestations. Case reports on the neurological manifestation of COVID-19 are increasing in the pediatric population. Case report In this study, a child suspected to Guillain-Barre Syndrome (GBS) associated with SARS-CoV-19 was reported. This case was a 31-month-old boy presented with transient dysautonomia, progressive symmetric muscle weakness in lower limbs, areflexia with a mild increase in the protein level of cerebro-spinal fluid and no significant evidence of inflammation. The results of an early electromyography-nerve conduction velocities were within normal limit at the fourth day. All radiological and laboratory findings were normal by considering possible causes. Intravenous immunoglobulin was administered, and clinical improvement was remarkable during treatment. Conclusion This case report represented an Iranian child with clinically diagnosed GBS, possibly triggered by SARS-CoV-2. It is recommended to consider COVID-19 in children with the neurological presentation in the current outbreak.
 

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Dear Editor
A catheter port is an implant that allows to frequenting and long-term access to the central vein. Using of central venous implant ports is increasingly day to day, because using of peripheral venous for frequent injections and continuous intravenous infusions is difficult.
In comparison of different catheters with each other, the port catheter has more advantages than the central venous catheter, such as decreasing the possibility of contamination with external pathogens. Central venous catheter, related to infections is a common cause of nosocomial infections acquired in children with cancer. Complications of port placement can doubt on parents and even health care personnel on its usefulness in children with cancer (1) .Because no studies have been done to assess complications of port catheter in the north of the country from 2007 so, the aim of this study was detection complication of port catheter in children with cancer and Satisfaction rate of parents was Satisfaction rate designed (2).

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Background and Objective: Determination of best preventive approach for gastrointestinal bleeding in Acute Coronary Syndrome (ACS) patients with high risk of gastrointestinal bleeding is crucial. This study aimed to determine the effect of pantoprazole on prevention of gastrointestinal bleeding in ACS patients with high risk of gastrointestinal bleeding.
Methods: This randomized clinical trial was performed in emergency department of Imam Hussein Hospital in Tehran, Iran between 2018 and 2019 among 1276 consecutive ACS patients with high risk of gastrointestinal bleeding.The participants were randomly received either pantoprazole 40 mg or famotidine 40 mg daily. The melena, hematemesis, hematochezia, and hemoglobin level were compared across the groups after one month.
Findings: The results in this study demonstrated that melena was seen in 1.1% and 3.8% in pantoprazole and famotidine groups, respectively with significant difference (P=0.002). Hematemesis was seen in 0.6% and 1.9% in pantoprazole and famotidine groups, respectively with significant difference (P=0.044). Also, hematochezia was seen in 0.3% and 0.8% in pantoprazole and famotidine groups, respectively without significant difference (P=0.452). The mean hemoglobin was 11.98 and 11.82 in pantoprazole and famotidine groups, respectively with significant difference (P=0.021).
Conclusion: This study showed that pantoprazole (versus famotidine) is effective for prevention of gastrointestinal bleeding in Acute Coronary Syndrome patients with high risk of gastrointestinal bleeding.

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Background: Traumatic brain injuries cause 14% of mortality in Iran. In this study we want to determine the relationship between laboratory findings and level of consciousness in patients with traumatic brain injury.
Methods: In this descriptive cross-sectional study, the data were collected by convenience sampling. 100 patients admitted to the emergency department of the 5^th Azar Hospital in Gorgan, were diagnosed with brain trauma. Blood samples were taken from these patients up to 24 hours after injury, and the demographic characteristics of the patients were collected in a checklist. Data were analyzed by SPSS16 software.
Results: The mean age of the patients was 26 ± 0.4 years. Laboratory findings in 100 patients included 73% leukocytosis, 60% increase in creatine phosphokinase (CPK), 82% increase in lactate dehydrogenase (LDH), 33% increase in ESR and 73% increase in protein acute phase (CRP). There was a significant and inverse relationship between the level of consciousness and the level of leukocytosis and creatine phosphokinase. Also, there was a significant relationship between the level of consciousness and acute phase proteins.
Conclusion: There was a significant correlation between the increases of three variables of parameters: leukocytes, creatine phosphokinase and acute phase proteins in patients with traumatic brain injury with decreased consciousness. Also, patients with higher level of consciousness and lower age had better prognosis. Due to the relationship between the level of consciousness and the Glasgow Outcome Scale, some laboratory findings can be used to estimate the level of consciousness and to determine the prognosis of traumatic injuries.

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Background: Many studies have proved the positive impact of public environment proportion on the quality of life of the elderly people. One of the environments that have appropriate effects for the elderly is religious places such as mosques. Therefore, the aim of this study is to develop a tool for structural fitness of age-friendly mosques, in a way that factors affecting the mosques to be age-friendly can be recognized through preparation of a standard checklist.
Methods: The components of the tool were developed through reviewing scientific literatures and sites. Measuring methods of face and content validity were used to investigate the validity of the research. The content validity was explored by employing a panel of 12 experts, including 4 individuals with PhDs in Gerontology, 4 Ergonomists, and 4 experts with PhD or Master’s degree in Civil Engineering. For the face validity, 20 individuals were surveyed, who were expected to complete the checklist when the project was operationalized. Cronbach's alpha coefficient was used to determine the reliability.
Results: The primary tool included 145 items in 12 domains, which were reduced to 121 items in 10 domains within the group discussion. Following the investigation of validity and reliability of the research, the number of final items of the tool was gathered in 80 questions. The mean of content validity index of the tool was calculated 0.96, Content validity Ration was greater than 0.56, and the Cronbach's alpha coefficient was 0.875.
Conclusion: The assessment tool of age-friendly mosques is available with appropriate validity and reliability to evaluate structural barriers in public places, including mosques. By studying the assessment tool, it is anticipated that the problems of access to the elderly in the mosque and other spaces would be identified and accessibility would be encouraged in the society.