en سندرم حاد تنفسی شدید کروناویروس 2 و عفونت همزمان ویروس آنفولانزا: دوست یا دشمن؟ ویروس شناسی ویروس شناسی مروری Review Article Currently, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the etiological factor of the coronavirus disease 2019 (COVID-19) pandemic condition. Based on the evidence, the number of infected patients is increasing around the world. SARS-COV2 infection could show both pulmonary and extra-pulmonary manifestations in patients. The Influenza virus is the cause of influenza disease which is a seasonal viral disease with clinical symptoms similar to COVID-19. Influenza could be a major public health problem throughout the world, as each year approximately 10%‐20% of the worldchr('39')s population are infected and is the major cause of death, particularly among the elderly. Since influenza has an effective and preventive vaccine, maximizing influenza vaccination has been suggested. Until now (November 20, 2020) COVID-19 doesn’t have any approved drug or vaccine, So the universal influenza vaccination will probably decrease the health burden of this co-infection. In this review, we will focus on the importance of COVID-19 and influenza co-infection in the COVID-19 pandemic era. SARS-COV-2, COVID-19, Influenza, Co-infection 16 26 http://crms.mubabol.ac.ir/browse.php?a_code=A-10-141-1&slc_lang=en&sid=1 Arghavan Zebardast arqavan9372@gmail.com 10031947532846002142 10031947532846002142 No Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran گروه ویروس شناسی، دانشکده بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایران Farzin Sadeghi sadeghifarzin6@gmail.com 10031947532846002143 10031947532846002143 Yes Cellular & Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran مرکز تحقیقات بیولوژی سلولی و ملکولی، پژوهشکده سلامت، دانشگاه علوم پزشکی بابل، بابل، ایران