Current Research in Medical Sciences

en Electrocardiography and echocardiography findings in infants of diabetic mothers: A case-control study قلب اطفال قلب اطفال پژوهشی اصیل Original Article Background: Gestational diabetes leads to various complications for the fetus, including heart abnormalities, and injuries during childbirth. This study aimed to investigate the changes of electrocardiogram (ECG), and echocardiography parameters in infants of diabetic mothers compared with those of healthy mothers. Methods: In this case-control study, 75 infants of mothers with controlled diabetes (case group) as well as 75 infants of healthy mothers (control group), who were born in Birjand Vali-e-Asr Hospital in 2021 were enrolled. ECG and echocardiography were performed for all infants, and the desired parameters (P, QT interval, QTd, QTc, QTcd, T, Tpe, heart rate (HR) as well as ejection fraction (EF), fractional shortening (FS), and IVSd) were measured. Results: The average QT interval and QTc parameters in the group of infants of diabetic mothers were higher than the healthy group (P≤0.01), while the average QTd in the infants of healthy mothers was higher than the infants of diabetic mothers (P=0.01). Furthermore, the average IVSd in the case group was higher than the control group (P=0.01). However, no differences in P, QTcd, T, TPe, HR, FS, EF, and heart axis parameters between the two groups were found (P>0.05). Conclusion: In conclusion, significant differences between the infants of healthy mothers and those with gestational diabetes regarding the parameters of QT interval, QTd, QTc, and IVSd were found. However, no differences in P, QTcd, T, TPe, HR, FS, EF, and heart axis parameters between the two groups were found. Therefore, it is a clinical necessity to examine and screen the infants of diabetic mothers via ECG and echocardiography.   Diabetes, Gestational, Heart Defects, Congenital, Pregnancy Complications, Echocardiography, Electrocardiography. 43 50 http://crms.mubabol.ac.ir/browse.php?a_code=A-10-188-1&slc_lang=en&sid=1 Forod Salehi فرود صالحی salehiforod@gmail.com 10031947532846001943 10031947532846001943 No Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran. Meysamreza Boghrati meysam.reza@gmail.com 10031947532846001944 10031947532846001944 No Clinical Research Development Unit, Vali-e-Asr Hospital, Department of Pediatrics, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran. Ali Fanoodi Fanoodi.af@gmail.com 10031947532846001945 10031947532846001945 No Student Research Committee, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran. Mahdi Ghoncheh mahdighoncheh@gmail.com 10031947532846001946 10031947532846001946 No Department of Plastic and Reconstructive Surgery, Department of Surgery, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran. Maryam Rezaei Dr.rezaei.maryam@gmail.com 10031947532846001947 10031947532846001947 No Department of Internal Medicine, School of Medicine, Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran Hamid Salehiniya alesaleh70@yahoo.com 10031947532846001948 10031947532846001948 No Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran. Hamideh Hajipoor Hajipourhamideh68@gmail.com 10031947532846001949 10031947532846001949 Yes Department of Internal Medicine, School of Medicine, Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran