Current Research in Medical Sciences

en Demographic, clinical and laboratory characteristics of pregnant women hospitalized with COVID-19 in the intensive care unit of Babol Ayatollah Rouhani Hospital علوم آزمایشگاهی علوم آزمایشگاهی پژوهشی اصیل Original Article Background: The COVID-19 disease is linked with several maternal and infant complications. Here, we conducted a study to examine the characteristics and outcomes of pregnant women who were admitted to the intensive care unit (ICU) due to COVID-19 complications. Methods: We performed a retrospective cohort study of symptomatic pregnant women with COVID-19 who were hospitalized at Ayatollah Rouhani Hospital, in Babol, northern Iran, from March 2019 to September 2021. We used a checklist to collect data from patient records, including maternal characteristics (age, body mass, gestational age, parity, blood type, residence, education, and comorbidities), disease symptoms, and laboratory criteria at admission and then compared these variables between pregnant women who required intensive care unit (ICU) admission and those who did not. We used SPSS 20 for data analysis and considered P<0.05 as significant. Results: We included 215 symptomatic PCR-positive pregnant women with COVID-19 who were hospitalized. The mean age of the women was 30.63±6.09 years and the mean gestational age was 27.77±9.96 weeks. The mean hospital stay was 5.38±5.20 days, and 21 (9.8%) women were admitted to the ICU for a mean of 6.28 ± 5.84 days. The levels of LDH and D-Dimer were significantly higher in the ICU group than in the non-ICU group (P-value<0.000 and P-value=0.024, respectively). The ICU group also had a higher rate of cesarean section (P-value<0.000). There were no significant differences between the groups in terms of clinical symptoms, demographic characteristics, Moreover, none of the women hospitalized with COVID-19 had renal, hepatic, or cardiac disease. None of the infants tested positive for COVID-19 by PCR. Conclusion: Our findings suggest that pregnant women with COVID-19 are not at increased risk of disease progression or ICU admission. Furthermore, we propose that monitoring the levels of D-Dimer and LDH in pregnant women with COVID-19 could be useful for predicting the severity of the disease and the need for ICU care, which may have implications for maternal and fetal outcomes.   Pregnant women, covid-19, intensive-care unit 13 20 http://crms.mubabol.ac.ir/browse.php?a_code=A-10-189-1&slc_lang=en&sid=1 Shahram Seyfi shahram.seyfi@yahoo.com 10031947532846002026 10031947532846002026 No Clinical Research Development Unit of Rouhani Hospital, Master of Science, Babol University of Medical Sciences, Babol, Iran Mahmoud Sadeghi drm_sadeghihz@yahoo.com 10031947532846002027 10031947532846002027 No Clinical Research Development Unit of Rouhani Hospital, Master of Science, Babol University of Medical Sciences, Babol, Iran. Azita Ghanbarpour a.ghanbarpour@yahoo.com 10031947532846002028 10031947532846002028 No Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Parviz Amri pamrimaleh@yahoo.com 10031947532846002029 10031947532846002029 No Clinical Research Development Unit of Rouhani Hospital, Master of Science, Babol University of Medical Sciences, Babol, Iran Mojgan Naeimi Rad mojy_rad@yahoo.com 10031947532846002030 10031947532846002030 Yes Clinical Research Development Unit of Rouhani Hospital, Master of Science, Babol University of Medical Sciences, Babol, Iran. Mina Galeshi galeshi_m@yahoo.com 10031947532846002031 10031947532846002031 No Student Research Committee, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran.